|Dosage and administration||
Dosage: The usual dose for long-term treatment is 1-2 tablets once daily. In some cases, the appropriate dose may be higher, especially in the short-term treatment and dose may be used up to 4 tablets per day as directed by doctor.
Hypersensitivity to salicylate derivatives and NSAIDs.
|Warnings and precautions for use||
Aspirin 81 is not suitable for use as an anti- inflammatory, analgesic, antipyretic.
|Recommendation for pregnancy and breastfeeding||
|Effects on ability to drive and use machines||
There have been no studies on the effects of Aspirin 81 on ability to drive or operate machinery.
|Interactions, incompatibilities of medicine||
|Undesirable effects (ADRs)||
Common, ADR >1/100
|Overdose and management||
Acetylsalicylic acid inhibits irreversibly cyclooxygenase, leads to inhibiting the synthesis of prostaglandin. Cells capable of synthesizing new cyclooxygenase may continue synthesizing prostaglandin after the concentration of acetylsalicylic acid is decreased. Platelets are cells that have no nucleus, they are unable to synthesize new cyclooxygenase, therefore cyclooxygenase is inhibited irreversibly until new platelets are formed. Thus, acetylsalicylic acid inhibits irreversibly platelet aggregation, until new platelets are produced.
After oral administration, acetylsalicylic acid is rapidly and highly absorbed. While absorbed in the gut wall, as well as in the liver and blood, acetylsalicylic acid is hydrolyzed to salicylic acid, which has the same pharmacological properties as acetylsalicylic acid.
|Storage conditions, shelf-life, quality specification of the medicine||
Storage conditions: Protect from humidity and light, below 30 degrees C.
Composition: Each enteric-coated tablet contains:
Acetylsalicylic acid. . . . . . . . . . . . . . . . . .81 mg
Box of 20 blisters x 10 enteric-coated tablets.
Primary and secondary prevention of myocardial infarction, strokes.