|Dosage and administration||
Hypersensitivity to dimenhydrinate or other antihistamines.
|Warnings and precautions for use||
Alcohol or other CNS depressants should be avoided because these drugs may increase hypnotic effects.
|Recommendation for pregnancy and breastfeeding||
|Effects on ability to drive and use machines||
Dimenhydrinate causes drowsiness. Avoid driving or operating machine if you are taking this medicine.
|Interactions, incompatibilities of medicine||
Dimenhydrinate may increase the effects of central nervous system depressants such as alcohol and barbiturates. Coadministration of dimenhydrinate and central nervous system depressants should be used with caution to avoid overdose.
|Undesirable effects (ADRs)||
Drowsiness is the most common undesirable effect of dimenhydrinate. Some undesirable effects of dimenhydrinate are associated with its anticholinergic effect.
|Overdose and management||
Dimenhydrinate is an antihistamine, sedative-hypnotic agent, belonging to the ethanolamine derivative group. It acts by competing with histamine for H1 receptor sites. Besides anti-histamine effect, dimenhydrinate also has anti-cholinergic, anti-vomiting and strong sedative effect.
Dimenhydrinate is well absorbed following oral administration, antiemetic effect occurs about 15 – 30 minutes following oral administration.
|Storage conditions, shelf-life, quality specification of the medicine||
Storage conditions: Protect from humidity and light, below 30 degrees C.
Composition: Each tablet contains:
Dimenhydrinate . . . . . . . . . . . . . . . . . . . . 50 mg
Cardboard box containing 1 blister of 20 tablets.
Prevention and treatment of nausea, vomiting, dizziness caused by motion sickness.
Symptomatic treatment of vomiting and vertigo in Ménière’s disease and other vestibular disturbances.